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Course Information

Pharmaceutical Medicinal Chemistry (CHE 323)

Term: Academic Year 2024-2025 Spring Semester

Faculty

Nicole Lynn Sciortino
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David Harry Dommer
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Schedule

Mon-Wed-Fri, 12:30 PM - 1:30 PM (2/3/2025 - 5/15/2025) Location: BART MOYE 110

Description

This integrated course provides a comprehensive overview of pharmaceutical and medicinal chemistry, focusing on the design, synthesis, analysis, and biological evaluation of drug molecules. Students will examine the physicochemical properties, structural activity relationships (SAR), and molecular mechanisms that underlie drug action. Topics include drug-receptor interactions, prodrugs, drug metabolism, and structure-based drug design. The laboratory component emphasizes hands-on synthesis, purification, and analysis of pharmaceutically active compounds using techniques such as recrystallization, spectroscopy, chromatography, and biological assays. This course bridges theory and practice to prepare students for careers in pharmaceutical sciences, drug development, and biomedical research.

Prerequisites: CHE 311 and CHE 312.